Sequencing of genomic α-gliadin clones from hexaploid bread wheat enabled to differentiate the sequences according to their loci Gli-A2, Gli-B2 and Gli-D2 based on genome-specific SNPs [16], [17].
Locus-specific primer pairs presented in this study are designed based on genome data of the Pacific bluefin tuna.
A genome-scale metabolic model, iJM658, was reconstructed based on genome annotation and literature mining.
39 There are also specific companies offering to scan and analyze parts of the human genome already known for susceptibility to diseases based on Genome Wide Association Studies GWASS).
Cas9 high-fidelity 2 (Cas9-HF2), which contains one additional mutation (D1135E) compared to Cas9-HF1 and exhibits altered PAM preference (from NGG/A to NGG only), has been proven highly specific based on genome-wide sequencing and targeted deep sequencing analyses (Kleinstiver et al., 2016; Kleinstiver et al., 2015).
Assessment of genetic diversity based on genome-wide SSRs and locus-specific candidate genes are complementary investigations, the former providing a global view of the rye genome and the latter restricted to genes involved in the frost tolerance network.
In addition to its current microarray data based on genome-wide tissue- and stage-specific gene expression, angaGEDUCI has been built with the goal of expanding its scope to house, integrate, and display additional microarray studies of An. gambiae.
Here we summarize the major reverse genetic approaches for loss-of-function studies used and emerging in zebrafish, including strategies based on genome-wide mutagenesis and methods for site-specific gene targeting.
The results are very similar to the results obtained from Dipteran insects based on the genome-specific frequencies of the codons (Behura and Severson 2011).
In Italy, swine influenza monitoring programs, based on specific genome detection, virus isolation, and molecular characterization of influenza viruses causing respiratory forms, have been in place since the 1990s.
These tools can query database independently to retrieve records based on a specific genome, specified combination of domains.
