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This finding suggests that QTLGLSchr8, which was thought to be a one major QTL based on genetic linkage analysis, most likely was represented by two QTL with lesser effects, further designated as QTLGLSchr8a (QTL8.2) and QTLGLSchr8b (QTable) (Table 4).
BRCA1 and BRCA2 were originally identified based on genetic linkage to families with an increased risk of breast and ovarian cancer.
In addition, GWAS revealed that QTLGLSchr8, which was claimed as a locus with major effect based on genetic linkage mapping, was likely to consist of two QTL.
Our data fit better the evolutionary models based on the advantage of coregulation than those based on genetic linkage or stochastic gene expression.
In the last decade a number the bovine genome maps have been published, many of them based on genetic linkage between markers [ 1- 3].
Already for decades, inheritance studies based on genetic linkage in families have been used to map genomic loci that have an effect on disease or other phenotypic traits.
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Previous studies had defined a segmental structure for the paleohexaploid Brassica genome based largely on genetic linkage of markers with similarity to sequences in the A. thaliana genome [ 9, 10].
In addition, Biofilter allows the investigator to include a subset of disease-related genes based on previous genetic linkage, genetic association, and gene expression studies.
Background: Effective gene mapping based on genetic association data will require detailed knowledge of patterns of linkage disequilibrium (LD) in human populations.
Conserved syntenies were identified based on genetic positions of BAC end associated microsatellite markers, the associated genes on the linkage map and model fish chromosomal locations.
These are not based on genetic knowledge.
More suggestions(16)
based on disulfide linkage
based on genetic programming
based on genetic identification
based on genetic influence
based on genetic distance
based on previous linkage
based on single linkage
based on genetic evidence
based on complete linkage
based on physical linkage
based on probabilistic linkage
based on genetic engineering
based on genetic improvement
based on genetic makeup
based on genetic information
based on high linkage
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