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To further assess the relevance of the proposed approach, we studied classification models based on genes that were detected by GSEA as significantly differentially expressed [9].
Our alignment was based on genes that shared the same stop codon, independent of having different start codons.
The present study provides a broad set of potential markers for subsets of subplate neurons, based on genes that putatively guide axons or support excitatory versus inhibitory connections.
We extracted a functional interaction network based on genes that show alteration in their expression profile during prostate cancer progression, limited to regulatory interactions which we define as the prostate cancer GRN (see " Methods" for details).
Based on genes that are conserved between D. pseudoobscura and the 10 Drosophila species outside the obscura clade (old genes), we determined the distribution of the fraction of the genes that could be aligned.
A principle component analysis (PCA) plot based on genes that differentiate MB and AT/RTs and AT/RT-like cases (with a positive false discovery rate (pFDR) threshold of q < 10−5, 496 probe sets) showed that the AT/RT and MB cases we diagnosed were distinct from each other at the mRNA level (Fig. 1d, Additional file 2).
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To our knowledge, no study has been able to decompose specialised functions of distinct brain regions based simply on genes that show enrichment within that region.
Considering that annotation for the bovine genome is not as accurate as for the human genome, the biological interpretation of selection signatures can be derived based only on genes that are located near candidate regions.
We derived a proliferation signature from in vitro microarray studies based only on genes that differ in expression in different parts of the cell cycle (Whitfield et al, 2002; Chang et al, 2004).
We turn our attention now to promising ecological frameworks based on gene exchange that may suit this purpose.
In fact, prognostic genes are beneficial for the development of risk scores based on gene expression, that can overcome the limitations of clinical prognostic factors [ 5, 6].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com