Sentence examples for based on gene sharing from inspiring English sources

Human disease and mouse phenotype gene sets are shown to group into disease and phenotypically relevant groups at both a coarse and fine level based on gene sharing.

Figure 2 shows a broad based dendrogram comparison based on gene sharing between 480 GAD disease gene sets, using gene sets each containing at least 3 genes.

The Drosophila gene set collection also produced a similar complex dendrogram of phenotypic functional groups based on gene sharing between gene sets.

Therefore, in addition to comparisons between individual diseases using human and mouse gene sets, we analyzed large gene groups using dendrogram and clustering approaches based on gene sharing between gene sets.

We are interested in the relationships between cyanobacterial species based on gene sharing, as compared to 16S rRNA analysis.

By contrast, claims that viruses form a group of organisms at the same level as cells and most specifically, that giant viruses form a fourth domain of organisms that can be placed in the tree of life based on genes shared by cells involved in typical cellular functions can be clearly refuted by proper molecular phylogenetic analyses.

Likewise, in branch 6 (Additional file 6: Figure S2) Dauer phenotypes are closely aligned with multiple lifespan phenotypes based on individual gene sharing within their respective gene sets.

Our alignment was based on genes that shared the same stop codon, independent of having different start codons.

This grouping of major disease phenotypes based solely on gene sharing provides supporting evidence that the underlying disease based gene sets may have a fundamental relevance to disease and may not be reported in the literature by chance alone.

The method combines microarray gene expression data with cancer prognostic information to identify synergistic gene-gene interactions that are then used to construct interaction networks based on gene modules (a group of genes which share similar function).

We also note that a disease similarity network can be constructed based on shared disease gene [30], shared pathways [35], shared miRNA [36], shared protein complex [37], shared disease ontology [38] and disease comorbidity [39].