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Gene symbols are manually curated based on gene function [ 23] and they are used by researchers to represent the same gene across different species.
Two (CYP27B1 and HOXA10) were selected based on gene function potentially related to fertility, and one (a non-CpG island reaction for IFNG) based on prior observation of hypomethylation in tumor versus normal tissue (data not shown).
For these reasons based on gene function and gene location, we considered SCARB1 as a good candidate gene for AMD.
The cancer-specific transcripts were classified based on gene function by searching the RefSeq database and GO.
In contrast to yeast, there is little evidence for clustering based on gene function in mammals [ 22].
Examination of genes at proximity of other signals of interest did not yield any obvious candidates based on gene function.
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Trait-based approaches offer a useful alternative, but many traits can be defined based on gene functions, metabolic modules, and genomic properties, and the optimal set of traits to choose is often not obvious.
Gene sets are usually defined based on gene functions, ontology information, chromosomal proximity or known regulatory relationships.
Based on gene functions, 127 differentially expressed genes were common to both semigametic anthers and ovules, with 115 being consistently differentially expressed in both tissues.
Figure 5a and b show the diagrammatic representation of P. falciparum phosphatases involved in various molecular functions and biological processes based on gene ontology function.
The gene attributes table also allows searches based on gene class, gene function annotations based on gene ontology (GO) [ 38], and protein domains.
More suggestions(16)
based on gene variance
based on gene set
based on gene deletion
based on gene expression
based on utility function
based on gene percentage
based on gene duplication
based on gene copy
based on gene structure
based on stream function
based on reaction function
based on product function
based on penalty function
based on gene architecture
based on saturation function
based on gene order
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