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Fig. 3 Pathogenicity of yeast isolates and commercial probiotic S. boulardii: a protease activity, b phospholipase activity and c haemolytic activity Fig. 4 Pathogenicity of yeast isolates based on gene amplification: a genomic DNA of the yeast isolates and b amplicons of yeast isolates.
HER2/neu status was determined based on gene amplification and/or immunohistochemical evaluation.
These figures may be improved if the selection criterion per patient is based on gene amplification rather than overexpression of c- erbB-2.
Current paradigms in trial design rely on genomic biomarkers, based on gene amplification or loss, or genetic mutations (Carden et al, 2010; Bauer et al, 2014).
Antitumor response rates can be maximized by selecting patients for treatment based on gene amplification tests (eg FISH) rather than on immunohistochemistry.
Miller et al. (2013) conducted a survey of AH activity in likely anoxic environments and in addition developed a genetic method of AH detection based on gene amplification from extracted DNA using a degenerate primer derived from P. acetylenicus.
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In the present study 28 Trueperella pyogenes strains isolated from various origins could successfully be identified with a newly designed loop-mediated isothermal amplification (LAMP) assay based on gene cpn60 encoding chaperonin.
In the present study 28 Arcanobacterium pluranimalium strains isolated from various origins could successfully be identified with a newly designed loop-mediated isothermal amplification (LAMP) assay based on gene pla encoding pluranimaliumlysin.
Another 7 transcription factor genes were annotated as having alternative transcripts with unique starting exons, based on gene-directed RT-PCR amplification, but for which EST supporting evidence (WormBase) was either weak or absent.
Additionally, a newly designed quantitative 5′ nuclease real-time multiplex PCR for Ehrlichia and Anaplasma spp. detection based on groEL gene amplification was designed, showing high specificity and sensitivity (10 groEL fragment copy/μL).
However, when patients are selected for trastuzumab therapy based on ERBB2/HER2 gene amplification, their response rate rises to as high as 50%.
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based on gene co-expression
based on gene set
based on gene expression
based on gene deletion
based on gene percentage
based on gene duplication
based on gene copy
based on gene structure
based on gene homology
based on gene architecture
based on oscillation amplification
based on gene order
based on kanamycin amplification
based on gene protein
based on gene essentiality
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