Samples were clustered based on "gain, normal, loss" (GNL) data, using an Agglomerative Hierarchical Clustering (described in Additional file 2).
Based on gain- or loss-of-function data collected in animal disease models using genetics or pharmacological modulation of microRNAs (miRNAs), it is now well accepted that miRNAs are important players during disease.
Now that you have written a frank and informative article about the reality that teenage sex happens early and often, based on data gained from three federally financed studies ("1 in 5 Teenagers Has Sex Before 15, Study Finds," news article, May 20), we can probably count the days before financing for such studies will be permanently curtailed.
Comprehensive and representative modelling of cave rock mechanics and geohydraulics based on data gained during field explorations, in situ tests, endoscopic investigations with borehole tools as well as by numerical modelling.
Inference on these systems based on data gained from clinical studies with several patient groups becomes a major challenge.
Please note that these calculations are based on data gained in vitro, so these can only be considered as rough estimates.
These studies, as well as the majority of global transcriptional analyses published so far, are based on data gained from in vitro parasite cultures and show only minimal differences across distinct parasite isolate strains.
The selected frequency represents the time pattern of loading during walking and the sine wave is a simplified load pattern based on data gained from patients with instrumented hip implants [ 65, 66].
Current treatment protocols for human glanders therefore, are based on data gained from treatment schemes for melioidosis, a disease caused by the closely related agent B. pseudomallei, using a combination of antibiotics for an extended period of time.
Follow-up 1 The participants will receive sleep advice and possible solutions focusing on behavioural strategies such as sleep hygiene, change of lifestyle, daily alcohol and caffeinated drinks consumption and activities before going to sleep, based on data gained from both parameters.
