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This decision was based on further profiling of VU0422288 in the Ricerca/Eurofins Lead Profiler panel of 68 different GPCRs, ion channels, and transporters; VU0422288 did not show activity at any of these targets.
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Although we still do not know what the connection of central and peripheral serotonergic changes in migraine may be, further study based on metabolic profiling of biological fluids which contain the "products of numerous genome-wide and proteome-wide interactions" [208], the 'metabolome' [209] will continue to shed light on the inner workings of the migraine brain.
5 The TNBC subgroup is also subdivided further based on gene expression profiling; this more in-depth classification may lead to better treatment selection.
The Parliament's Consolidated version adds further categories of information to this list: 14(1)(ga): 'where applicable, information about the existence of profiling, of measures based on profiling, and the envisaged effects of profiling on the data subject'.
Genes encoding non-transcription factor (NTF) proteins (2,456) were further classified based on expression profiles to establish the composition of various co-expressed groups (regulatory clusters) controlled by the different classes of TFs listed in Table 1.
Further based on the expression profile four transgenic lines with differential transcript levels were selected to assess the seed viability and seedling vigour (Fig. 4a).
This dose was further based on the pharmacokinetic/pharmacodynamic profile of inhaled THC (Zuurman et al., 2008).
It is not discrimination based on racial profiling.
Species identification was based on biochemical profiling.
Further studies, including studies based on comparative gene profiling strategies, are required to better define the likely complex molecular machinery that links KRIT1 to FoxO1 functions.
By further classifying E genes based on expression profiles, we were able to discern the functional specificity of transcriptional responses at particular stages of water-deficit, noting both the well-known reduction in photosynthesis genes as well as the less understood up-regulation of the protein transport pathway.
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