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We developed a theoretical model of single-stage thermal modulation processes based on fundamental physics of gas chromatography (GC) with the aim to elucidate factors leading to improvements in GC × GC analyses.
An important difference arises between models like this, which are based on phenomenology and guesswork, and models based on fundamental physics.
The energy balance equation is based on fundamental physics and cannot itself be wrong, but its application in obesity research is increasingly considered problematic (Lustig, 2006; Taubes, 2008; Wells and Siervo, 2011).
At this point, we do not want to enter the intensive debate conducted in philosophy and science concerning the question whether or not the entire world could at least "in principle" be described based on fundamental physics.
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More sophisticated quantitative models describing, for example, the movement of molecules across a cell membrane in terms of mathematical equations based on fundamental laws of physics—have also been employed for decades.But there is only so much insight, and so many hypotheses, to be gleaned from simple models.
These types of applications — real-world applications based on fundamental advances of physics — keeps me thinking, and up at night.
An elementary approach is illustrated by an accompanying simulation computer program and supported by a mathematical treatment based on fundamental laws of physics and conservation laws.
The security of quantum communication (Q.Com) is based on fundamental and immutable laws of physics and not on the assumption that a problem is and always will be too difficult for an adversary to solve.
That being said, there are several approaches (adhesion-based, dielectrophoresis, optical/FACS) that have inherently low ceilings with respect to throughputs based on fundamental limits imposed by the either the chemistry and/or physics of the platform.
Mass action is not physics or even chemistry, it is phenomenology: a mathematical formulation, which may account for observed behavior but which is not based on fundamental laws.
All comparisons were based on fundamental frequency patterns, not harmonics.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com