Sentence examples for based on functional similarity from inspiring English sources

We excluded text mining-based networks to avoid confounding by links based on functional similarity.

Analyses of candidate gene groups based on functional similarity revealed three groups that were associated with at least one cachexia phenotype at the p < 0.05 level (Table 3).

Of the ten methods studied in our analysis, only four (RBH, Inparanoid, OrthoMCL and KOG) were included in that study: rankings in sensitivity (approximated indirectly as raw numbers of ortholog predictions) and specificity (inferred indirectly based on functional similarity score) partly agree with the present report.

Pathways were arranged into a tree based on functional similarity, shown on both axes.

These applications were grouped into 7 categories based on functional similarity: disease diagnosis, drug reference, medical calculators, literature search, clinical communication, HIS clients, and medical training.

However, these gene names are not necessarily based on functional similarity with ScTor1 and ScTor2 but rather indicate only that there are two TOR homologs in B. dendrobatidis.

Comparison of gene responses, based on functional similarities, not surprisingly, showed many up regulated genes coding for inflammatory mediators (Fig. 3).

Broadly, β-galactosidases are classified into seven glycoside hydrolase (GH) families based on functional similarities [ 10], with the extensively studied E. coli enzyme belonging to the GH-2 family [ 11].

Functional gene classification analysis generates gene-to-gene similarity matrix based on functional annotations associated with each gene and classifies genes into functionally related groups.

In the second step, candidate proteins are extracted based on their functional similarity to the seed set and a domain-specific similarity network is generated by extending this set by all functionally related proteins.

In order to answer this question, we constructed a comprehensive network of human genes based on their functional similarity, where each interaction is between two genes sharing a significant functional annotation from either Gene Ontology [ 17] or KEGG [ 18] (the Fun-Net, see Methods).