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TRIZ based Function Analysis models existing products based on functional interactions between product parts.
Networks are generated not only based on functional interactions but also statistical likelihood.
Our goal was to extend our results beyond lists of genes and ontological classifications to discover new pathways based on functional interactions.
The authors created genetic networks based on functional interactions between the 418 genes of yeast for both the untreated and the MMS-treated conditions and observed that from the 3126 unique interactions present in any of the two networks, 2050 (65.56%) were condition-specific, demonstrating that the sole addition of a DNA-damaging chemical agent produces a massive rewiring of the network.
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AIR is based on functional interaction of the fungal transactivator AlcR and AlcR-specific chimeric promoters (PAIR) which drive desired transgene expression in mammalian cells only in the presence of gaseous acetaldehyde.
A global view based on functional molecular interactions illustrated an intricate network of paths associated with both apoptosis and proliferation/cell survival.
A series of 2-variable, 3-variable, and 6-variable models, based on functional variations on, and interactions between, the PCS-12 and MCS-12 were developed.
In recent years, a number of recognizing disease gene approaches and computer tools have been developed through building mathematic models based on functional annotation, sequence-based features, protein interaction, and disease phenotype [ 7– 16], such as sequence features [ 15], functional annotation [ 7, 8, 10, 13], and physical interactions [ 12, 13, 17].
Self-administered training at home is performed through repetitive interaction with games based on functional exercises (rehabilitation games) to enhance engagement.
In this study, we perform systematic analysis of DDIs based on functional group of drugs and construct the network which consists of interactions among the drug groups (DGs).
Analysis of the protein networks was performed by using Ingenuity Pathways Analysis (Ingenuity Systems, Redwood City, CA), software able to identify molecular networks based on known functional or physical interactions among the proteins encoded by the differentially expressed genes.
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