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These data are summarized in Figure 3 based on functional groups of GO biological process (information in GO molecular function and cellular component for each gene is also presented in Additional file 1: Table S1), distinguishing genes showing increased or decreased expression using different colors.
The SQ-29852 molecule was divided into six binding domains (A F) based on functional groups within these regions and the effects of structural variation in four of these domains (A, C E) were explored.
In the tertiary level, the classification is based on functional groups like alcohol, ketone, aldehyde, ester, etc. and broad classes like steroid, terpene, triterpene, sesquiterpene, sugar, furan, etc.
One can combine a number of defined substructures to produce more complicated substructures, and can search for enzymes based on functional groups.
Analyses based on functional groups can remove 'noise' and simplify system modelling and monitoring, but phylogenetic details remain important.
Since we wish to unravel the global properties of the reactome, we want to keep our representation as simple as possible (i.e. not based on functional groups) so that the kind of results we can obtain is not restricted.
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Although, there were differences in the functional diversity estimates between the analyses based on functional group and trait data, the overall findings of our study were robust to the type of information used to describe function.
The results point to naturally occurring branched molecules in the nC9 nC13 range which, coupled with our prior results based on functional group allocation, suggest that ester or other carbonyl moieties in these components inhibit clathrate hydrate plug build-up.
In this study, we perform systematic analysis of DDIs based on functional group of drugs and construct the network which consists of interactions among the drug groups (DGs).
Based on functional group analysis, Varroa-infested bees show decreased expression of glutamate and GABA receptor-related genes, the dopamine receptor, Amdop1, and overexpression of ascorbate/aldarate metabolism genes.
> -wrap-foot> The aforementioned analysis based on functional group conversion hierarchies is extended to include the RPAIR data provided by KEGG on a sample mapping pair provided by both algorithms executed on the amino acid metabolism networks of the atc-eco pair.
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based on functional principles
based on functional requirements
based on hydroxamic groups
based on ethnic groups
based on functional networks
based on functional pathways
based on functional equations
based on generic groups
based on monophyletic groups
based on functional markers
based on functional areas
based on functional tests
based on individual groups
based on functional reviews
based on large groups
based on functional relationships
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