Sentence examples for based on functional enrichment from inspiring English sources
Using the disease-gene, drug-target, and the enriched features of diseases and drugs (based on functional enrichment analyses of diseases and drugs), we built a gene and feature-based network where nodes represent disease or drug while the edges represent shared gene and/or enriched features (biological process, mouse phenotype and pathways; p-value ≤0.05 Bonferroni correction).
Canker-module 25 was selected based on functional enrichment analyses.
Flesh-module 19 was also selected based on functional enrichment analyses.
These DEGs were first classified by GO annotations, then hand-curated and assigned into different gene networks based on functional enrichment results and prior knowledge of the genes.
Based on functional enrichment analysis of genes showing accelerated rates of mutation towards translationally inefficient codons, we suggest this selection may be acting to minimize stochastic noise in gene expression.
All interpretations based on functional enrichments must be treated with caution as the annotations are far from complete or even up to date.
Based on functional-enrichment analysis, the apoptosis pathway is significantly involved in the saliva-deposition response.
The Functional Classification Tool in the Database for Annotation, Visualization and Integrated Discovery (DAVID; http://david.abcc.ncifcrf.gov/) [ 27, 28] was used to group proteins based on functional similarity and to determine enrichment of functional protein groups within the total set of differentially expressed proteins.
Focusing on the 52 sweeps containing only one gene, we performed a gene set enrichment analysis based on functional annotations.
We used hypergeometric test to calculate the enrichment significance based on functional context.
Using ClueGO (v2.1.3) plugin, [ 79] we performed an enrichment analysis based on functional classifications available at Kyoto Encyclopedia of Genes and Genomes (KEGG) [ 80], Reactome [ 81] and Gene Ontology (GO) [ 82], using the complete set of probes of 32 K cDNA microarray as reference.
