Vice versa, one parent was found to be QTL heterozygous based on fry data but not on post-smolt data, although it was close to being declared QTL heterozygous in the post-smolt test as well (P = 0.051).
Chemometric tools were used to classify the oil samples based on frying stability.
To measure the frailty of people 75 years or over and who live in their own homes based on Fried's criteria and modified by Ávila-Funes.
Our definition of nonfrail subjects was based on Fried criteria (Bouillon et al., 2013).
Included studies used an explicit biological definition of frailty based on Fried et al's criteria and a screening measure to identify depressive symptomatology.
The position of the QTL based on fry data corresponded well with the position based on post-smolt data, the 95% confidence interval for position being at 19 26 cM.
Of these, two studies performed ROC curve analysis and showed AUC, based on Fried's phenotype and SOF index, ranging from 0.61 to 0.63, which was comparable with our result using FI (AUC = 0.62) [ 11, 12].
In the SHARE study, frailty was measured using the SHARE-FI, an instrument based on Fried criteria [ 7] but using different components e.g. walking speed was measured by self-reported items related to mobility limitations and not objective measurement such as gait speed or the timed up and go.
In a systematic review comparing and pooling international frailty prevalence data, although estimates varied widely, the overall weighted average prevalence of frailty was 9.9% (range 4.0%-17.0%) in community-dwelling adults aged 65 years and over using definitions of frailty based on Fried criteria [ 26].
Of note is that a large scale population-based survey in Japan reported a frailty prevalence of 11.3% based on the Fried phenotype among community-dwelling adults aged 65 years and older, which was slightly higher than the prevalence in our study [ 15].
