Sentence examples for based on frameshift mutations from inspiring English sources

Predicted pseudogenes based on frameshift mutations or stop codons within the first 100 aa of the coding sequence have been excluded from the table.

Three major NOD2 variants are associated with CD; two missense mutations, R702W and G908R, and one frameshift mutation, L1007fsinsC.

First, we detect possible deleterious mutations in an individual based on pathogenic mutation database from MITOMAP.

Based on their high mutation frequency, SLC35F5, ARV1, TTC3, and SMAP1 represent new target genes in which frameshift mutations have not previously been reported in MSI CRC.

SNVs were prioritized based on loss of function mutations (nonsense, frameshift, splice sites) and damaging missense mutations that fit an autosomal recessive disease model.

This predicted pathogenicity was based on the type of mutation (frameshift) or on the results obtained from in vitro functional analysis.

This is based on the idea that nonsense mutations and frameshifting mutations usually generate null alleles.

In our mutation studies (A131), we found that a recB mutation completely blocked the formation of long deletions, while base substitution and frameshift mutations were little affected.

The spectrum of CAN1 mutants indicates that exposure to Mn results in accumulation of base substitutions and frameshift mutations.

The presumed halothane metabolite, 2-bromo-1,1-difluoroethylene, produces both base substitution and frameshift mutations in Salmonella typhimurium.

MNNG induced Al, mutation to 6-thioguanine resistance, and mutation to ouabain resistance, and might induce Al by base substitution or frameshift mutations.