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The first step involves the identification of object resources based on file structure and hyperlinks.
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We present a microarchitecture solution based on a register file holding basic blocks of instructions.
Homology modelling of TrkA TK domain, based on 1luf structure file, allowed us to visualise the localisation of His604 relative to the domain's functional regions.
In contrast, PCA generated different cluster types in the same sets of individuals based on population structure (Additional file 4: Figure S4).
Since by selection the CSEPs had little sequence similarity (BLASTP, e<10-05) to any protein previously structurally or functionally characterized, we carried out structural annotation using protein fold recognition methods [ 11], to search for potential relationships based on predicted structure (Additional file 15).
For this purpose we generated molecular models of the compounds based on structure data files (sdf) using LigPrep, a ligand preparation tool that is interfaced with Maestro (Schrodinger Inc. NY).
The selected model for Ns-AtpG (Additional file 7: Figure S6F, Additional file 8) is based on the template structure 2K88 (Additional file 6: Figure S7B) and is similar to canonical AtpG structures with a long helix with breaks only towards the ends.
To meet the IS domain, a structure for the presentation of patterns was established (Additional file 1) based on the structure of Gamma et al. (1994) and Withall (2007).Some elements have been added such as domain, type, and related patterns.
gBSDtoBin: This part generates the final adapted media file based on the adapted structure from Description transformation.
Hidost has been designed as a malware detection system capable of learning to discriminate between malicious and benign files based on their logical structure.
With this in mind, Hope uses an array of state-of-the-art modeling, tweaking, and printing tools to make multi-colored, chaotic Qubit-Built Quilts based on nanoscaled structures, Protein Data Bank files, nanomolecular machine components, junk DNA, sheets of graphene, bucky-balls, and carbon nanotubes.
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