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The strains to use must be selected with care and based on extensive preclinical.
Based on extensive preclinical modeling, we have translated our intratumoral DC-AdCCL21 approach to treat advanced stage lung cancer in a phase I clinical trial.
Development of endostatin has been undertaken for the treatment of gliomas based on extensive preclinical data [ 35].
The early enthusiasm for incretin-mediated preservation or enhancement of β-cell mass and function was based on extensive preclinical studies predominantly in rodents and complemented by studies using cell lines and islets (3, 4).
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Every decision is based on extensive legal and policy advice.
Their structures were characterized based on extensive spectroscopic data.
The new structures were characterized based on extensive spectroscopic analysis.
Design guidelines are drawn based on extensive simulations.
A conceptual model was developed based on extensive literature review.
Based on extensive parameter studies, faultless joints were produced.
Its unusual shape is based on extensive ergonomic research.
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