Recent efforts have focused on immuno-PET, which uses antibody-based radiotracers, to image tumors based on expression of tumor-associated antigens.
Until recently, human monocytes were subdivided based on expression of the surface marker CD16.
Comparative studies of monocytes in mice have yielded more dichotomous results based on expression of the Ly6C antigen.
Figure 1 Sample gating strategy showing three human monocyte populations based on expression of CD14 and CD16.
However, the strains were based on expression of different heterologous xylose and acetoacetyl-CoA reductases, with different affinities for the co-factors NADH and NADPH (Fig. 1).
The results from these studies suggest personalized therapy selection based on expression of genes associated with chemoresistance can be used to increase patient response.
CD4+ T cells were measured by flow cytometry based on expression of CD4; Treg cells were identified based on expression of CD4, CD25, and CD127, and results were expressed as the total number of Treg cells and as the proportion of the total number of CD4+ T cells.
Alternatively, tissue-specific precursors can be sorted using fluorescence-activated cell sorter (FACS) based on expression of specific markers on the cell surface.
We have developed a model based on expression of the mDUX ORF during Xenopus development.
Figure 3 shows sample unsupervised hierarchical clustering (Pearson's correlation) based on expression of all known and predicted miRNAs.
The tauopathy model used in the current studies is based on expression of human tau in Drosophila.
