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Using previously published expression data the effect of transcription on gene-body methylation was investigated and while X-linked introns of highly expressed genes were more methylated than the introns of lowly expressed genes, exonic methylation did not differ based on expression level.
Based on expression level, CEACAM6 may be a more promising target for antibody-based anti-metastatic and chemosensitizing therapy than CEACAM5 in all the solid tumors studied.
Based on expression level and SUR1-Kir6.2 tetrassemblyembly, SUR1-Kir6.2 fusion with a 39-residue linker (VDGSGSGSGSAAGSGSGSGSGSGAAGSGSGSGSGSGAAA) was selected and expressed in BacMam system for further structural characterization (Goehring et al., 2014).
Differentially expressed genes (DEGs) catalog of Agrobacterium mediated transformation calli to their corresponding non-treated samples is helpful to identify candidate genes responsible for T-DNA or transposons integration into genome based on expression level.
The data were filtered based on expression level changes of greater than 1.5-fold.
Genes represented on the microarray were ranked by expression level and divided into 4 bins based on expression level.
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A diagnostic model based on expression levels of ten miRNAs is constructed in the discovery set.
Based on these findings, a clinical trial for anti-PD1 (pembrolizumab) was conducted where NSCLC patients were screened based on expression levels of PD-L1 on the primary tumor7,14.
Based on expression levels of the top-ranked genes, we chose Col4a1/a2, encoding the alpha-1 or alpha-2 chain of type IV collagen, for the reporter gene in our shRNA screening (Figs 1A and S1B).
Alleles were selected based on expression levels in silico, possible ER/Golgi localization and the availability of T-DNA lines.
Alternatively, autosomal genes may regulate imprinting based on expression levels of heterosomal genes.
More suggestions(17)
based on expression profiling
based on water level
based on expression evidence
based on expression spontaneity
based on expression similarity
based on expression enrichment
based on asset level
based on transcript level
based on expression perturbation
based on payroll level
based on ability level
based on expression style
based on phylum level
based on expression randomisation
based on education level
based on voltage level
based on expression signature
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