Sorting ObL cells based on expression of ALP, a well-established osteoblast marker, allows enrichment for immature versus more mature osteoblastic precursors [23].
In our study we detected CTCs by qRT-PCR methods based on expression of KRT19 and EMT-TFs respectively with pre-enrichment step utilizing CD45 negative selection, unfortunately, CD45 depleted cells do not necessarily contain only CTCs.
In addition, Peh et al. have reported the enrichment for neurosphere-forming NSC from neural induction cultures of hESC based on expression for CD133, CD15 and GCTM-2 [28].
Qqplots illustrate the enrichment of low synergistic interaction observed p values (black), together with the 5th and 95th confidence limits based on expression permutations (gray) with respect to the expected uniform distribution.
Strategies for enrichment have included manual dissection of beating areas [10], [11], Percoll® density gradient sedimentation [7], [12], and fluorescence activated cell sorting (FACS) of cells based on expression of a fluorescent reporter protein from cardiomyocyte gene promoters [11], [13].
This database contains a collection of 7,261 tissue-specific genes from 30 tissues based on the expression enrichment (EE) values and statistical significance.
The selection was based on the expression enrichment score, which was defined as the ratio between observed and expected number of ESTs for a gene.
In the UAE, we have embarked on a program to transform our economy from one based on resource depletion to one based on resource enrichment.
The annotation table was further used to implement a functional genomics analysis of gene expression data based on the enrichment of GO terms associated with differentially expressed genes (DEGs).
We proposed a profile-based approach to characterize a disease using a binary vector whose elements indicate whether a given function is perturbed based on the enrichment analysis of expression data between normal and tumor tissues.
