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Based on experimental models, it has been hypothesized that PM-soluble components are one of the major suspected culprits of the neurological effects of air pollution, primarily metals, because they may translocate from the respiratory tract into the systemic circulation and reach the fetus and promote oxidative stress and inflammation (Block et al. 2012).
Recently, we have introduced a novel methodology based on experimental models, when tissue sections from untreated animals were deposited with or submerged in drug solutions prior to MALDI-MS imaging analysis [25, 26].
Although consistent evidence based on experimental models and human P. falciparum infection suggest that Tregs may contribute to the onset of infection, the role of these cells during malaria and the possible mechanisms of regulation are not yet fully elucidated.
Several mechanisms have been proposed that are based on experimental models (reviewed by [ 1, 17]).
In addition, our study contributes to knowledge on particular symptoms of shigellosis associated with virulence genes, whose information about their roles are based on experimental models.
Since the hypotheses concerning chromosome breakage are based on experimental models, the comparison with data from patient material provides an essential verification.
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Cellobiose production from Avicel hydrolysis based on experimental and model simulation data were in qualitative and quantitative agreement at 25 and 50 g/L Avicel loadings.
Recent evidence based on experimental animal models shows that enhanced intrarenal angiotensinogen formation during angiotensin II infusion is reflected by secretion into the tubular fluid leading to increased urinary angiotensinogen [ 6, 7].
Based on experimental rabbit models (Ghanem et al. 2009, Widmann et al. 2010, Moon et al. 2012), epiphysiodesis using radio-frequency ablation (RFA) is a successful minimally invasive method.
Specifically, the year-wise analysis of α-HCH contaminant flow direction based on experimental variogram modelling predicted a prominent flow direction towards the North in 2006 which verified the groundwater and contaminant flow direction observed from the hydrogeological modeling.
Combined with statistical validation based on experimental data, dynamic models can serve as a platform for testing hypotheses e.g. on pharmacological interventions on the system.
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based on experimental results
based on economic models
based on old models
based on demographic models
based on synthetic models
based on French models
based on experimental studies
based on successful models
based on other models
based on poetic models
based on micromechanical models
based on predictive models
based on experimental approaches
based on industrial models
based on experimental tests
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