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Possible in-paralogs within the polyploid species were reduced to one representative sequence based on evolutionary distance.
The similarity between the sets can be measured based on evolutionary distance metrics, e.g. hamming and edit distance (also called Levenshtein distance, see Methods).
The mapping of TFs between genomes based on evolutionary distance has been investigated in our previous work using bacterial genomes [ 16].
Orthology detection methods, based mainly on phylogeny, and implemented in software such as RIO [ 3], Orthostrapper [ 4, 5], PhiGs [ 6], PhyOP [ 7], TreeFam [ 8], or based on evolutionary distance (RSD [ 9, 10]), generally do not erroneously report genes as orthologous (false positive, FP), but have a high frequency of missed orthologs (false negative, FN).
Here, we integrate sequence data obtained by shotgun community genome sequencing approaches (metagenomics) [ 13, 14] with tools that enable sequence clustering based on a Markov clustering algorithm [ 15] with BLAST homology [ 15- 17] to categorize metagenomic reads based on evolutionary distance [ 18- 21].
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In previous studies, similarities of evolutionary histories between two molecules were estimated based on evolutionary distances across different species or namely phylogenetic trees.
The best scores of both indices should allow to identify the more diverse PCGs in a approach complementary to the usual method based on evolutionary distances among orthologous sequences (e.g. [ 8]).
The UniFrac metric is a proxy for the distance between microbial communities based on evolutionary relatedness of lineages in each sample.
JET [ 23] builds off the evolutionary trace approach [ 177- 180], constructing phylogenetic distance trees to extract a residue ranking based on evolutionary importance, then using this to derive likely PPISs.
These forms are based on evolutionary considerations, while for our approach, which is based on the present state of correlations, the Hamming distance is the metric of choice.
The second is based on Evolutionary Algorithm.
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based on evolutionary computing
based on local distance
based on evolutionary approach
based on evolutionary algorithm
based on evolutionary process
based on geometrical distance
based on Euclidian distance
based on physical distance
based on evolutionary change
based on evolutionary analysis
based on evolutionary game
based on evolutionary relationship
based on evolutionary search
based on evolutionary optimization
based on Euclidean distance
based on evolutionary strategy
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