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For more than a decade, operative decisions (resection plus anastomosis vs diversion) for colon injuries, at our institution, have followed a defined management algorithm based on established risk factors (pre- or intraoperative transfusion requirements of more than 6 units packed RBCs and/or presence of significant comorbid diseases).
We examined the following predictor variables based on established risk factors for cardiovascular disease and heart failure.
16 We examined predictor variables based on established risk factors for venous thromboembolism, focusing on those that are likely to be recorded in the patient's electronic record and that the patient is likely to know (box 1).
We examined the following predictor variables based on established risk factors for each cancer as determined in other studies 14 17 or listed on the Cancer Research UK website.
While assessment of risk of bias is controversial for the evaluation of non-randomised designs, the use of a robust quality appraisal framework based on established risk of bias assessment for randomised trials and critical appraisal tools for non-randomised studies 30 34 65 was a significant strength of the present review.
Similarly, for about 46.1% of the controls who were initially estimated to have 1.5%to<2.0%0% risk based on established risk factors only, the new model with GRS indicated a lower risk of 1.0%to<1.5%5%, while shifting 12 individuals to the 2.0% to <2.5% risk stratum.
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The calculating score was based only on established risk or protective cancer factors.
Incorporating the four biomarkers significantly improved the prognostic value of a model based only on established risk factors such as age, blood pressure and hyperlipidemia.
We used the Archimedes Model to simulate a clinical trial of individuals (N=11,000) with diagnosed type 2 diabetes and elevated CV risk, based on established disease or multiple risk factors.
We consider it our public health responsibility to at least qualitatively consider recent toxicologic data in addition to a quantitative risk assessment based on established reference values.
We constructed three childhood lead exposure risk models based on established methods but using different levels of geocoded data from blood lead surveillance, county tax assessors, and the 2000 U.S. Census for 18 counties in North Carolina.
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based on established engineering
based on adjusted risk
based on defined risk
based on established network
based on established model
based on established relationship
based on established categorization
based on established flow
based on established material
based on established case
based on established neurophysiologic
based on established phonon
based on established information
based on established planning
based on established lore
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