These sophisticated interactions differ among individuals based on environmental factors.
Mate selection is purely based on environmental similarities.
As an example for using PG- and TR-based methods based on genetical genomics data see [ 50].
Candidate genes were selected based on comparative genomics and gene expression analysis, which we evaluated with association and linkage mapping.
Therefore, reverse genetic approaches based on functional genomics might be quite useful.
Despite this drawback, several regulon databases are available that are based on comparative genomics methods and lack experimental evidence.
The analysis below (Table 2, and references therein) is hence mainly based on comparative genomics predictions that await experimental validations.
We carried out a novel bioinformatics screen for other possible dual-frame translated sequences, based on comparative genomics.
Based on comparative genomics, crcB has been found in Archaea and Bacteria, and TPP and flp in Euryarchaea [ 60, 62].
We provide experimental evidence at the molecular level based on a genomics approach to support the metabolic stability hypothesis.
