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Tail damage development is therefore a better way to analyse the effects of external and internal factors that result in tail biting, compared to methods based on end point analyses.
The results for MYH7 RNA expression based on end point PCR as compared to real time PCR were similar (Fig 1c vs. 1e).
Based on end point 8-point SMBG profiles, there were no differences between combined LY2605541 and GL daily mean BG (SMBG) (Table 2) or most categorical SMBG time points at end point, although, a significantly greater reduction from baseline in daily mean BG was observed with combined LY2605541 versus GL (P = 0.017).
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The safety and tolerability of canagliflozin was assessed based on end points described in the next section.
The present study further demonstrates the feasibility of an end point of type (2) and demonstrates the feasibility and practicality of clinical trials based on end points of types (3) and (4).
Considering that the majority of mixture studies have been based on end points relatively close to the steps following hormone-receptor binding and activation, the choice of dose addition appears to be well-founded.
Therefore, Tier 3 in the in vitro alternative predictive test batteries strategy, based on end points, mechanisms, and processes relevant to DNT for chemical-induced neurotoxicity, might be of great added value and become increasingly more important for regulatory decision making.
In order to actively suppress the link vibrations excited during the trajectory-tracking phase, a second controller based on end-point sensing and the rigid Jacobian of the manipulator is used.
Internationally human enteric viruses, such as norovirus (NoV) and hepatitis A virus (HAV), are frequently associated with shellfish related foodborne disease outbreaks, and it has been suggested that acceptable NoV limits based on end-point testing be established for this high risk food group.
To compare the relative number of transcripts of samples taken at different time points, real-time RT-PCR is a better method than 5'-RACE because 5'-RACE is based on end-point PCR reactions.
aValues are stated as medians (range in parentheses) based on end-point dilution.
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