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Some researchers theorized, based on early sequencing data, that EBOV had circulated for decades, undetected, in animals in the region.
An RT-PCR for detection of pandemic (H1N1) 2009 virus was developed based on early sequencing data (EpiFlu Database, http://platform.gisaid.org).org
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These datasets consisted of cDNA predictions based on early drafts of genome sequences for 13 mammalian species.
Based on early genomic studies, it was concluded that different species have a unique sequence composition, which has been named 'genomic signature' [ 19].
The earliest of these were based on Early Christian models.
Based on earlier analysis of expressed sequence tags (ESTs), over 50% of the human and more than 30% of mouse genes were observed to have multiple polyadenylation sites, which results in mRNA isoforms different in their 3′-UTR and/or coding sequences (Tian et al., 2005).
Based on earlier unpublished work 50 authentic EhSINE1 sequences had been identified by BLAST searches [ 34] of the original eha1 E. histolytica genome assembly http://www.tigr.org/tdb/e2k1/eha1/[ 35] and each one examined in detail to determine the number of repeats present.
Based on earlier observations on the major effect of sequence variation of PCSK9 gene on plasma LDL cholesterol concentrations and coronary heart disease risk and the result of the current study, PCSK9 seems to be an interesting new target molecule for the development of new antiatherogenic therapies.
This proposed pathological sequence is in fact based on earlier autopsy literature [ 6, 9, 32].
As genetic sequencing becomes more common in research, recruitment of participants based on earlier genetic research results becomes of greater importance.
HumanGPCR sequences were identified using GPCRDB [ 30] (Release 8.1) and based on earlier studies [ 7, 19, 23, 31].
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