Sentence examples for based on early response from inspiring English sources
The proposition links drug-induced neural and behavioral changes of antidepressants with prediction of clinical outcome based on early response.
Whether an abbreviated assessment such as this can be used to predict longer term response based on early response to olanzapine LAI will need to be determined.
Also, antipsychotics are most effective in treating positive symptoms, so a model that predicts later response based on early response is likely to include them.
The GeparTrio trial [5] investigated a response-guided approach based on early response assessment; the treatment was either intensified with two additional cycles in the case of an early response, or changed to a different chemotherapy in the case of no response.
Although the results of the first trials have been published in which the performance of individually tailored therapy based on early response to neoadjuvant treatment is investigated [ 6] and new trials are currently being undertaken, the multiple factors influencing the quantification of glucose metabolism by FDG PET are still under discussion [ 7– 9].
6 8, 12 25] provided a reliable basis for several (ongoing) clinical trials in patients with Hodgkin lymphoma and aggressive non-Hodgkin lymphoma, which investigate the value of treatment adaptation based on early response monitoring using interim FDG-PET (Tables 1 3).
Post hoc analyses to predict the proportion of CZP-treated patients who achieved DAS28 ESR) LDA (≤3.2) at week 28 based on early responses were also conducted, stratified by prior anti-TNF experience.
This trial explores the course of and factors associated with HRQL in patients given individualized or standard treatment based on early treatment response (Ditto-study).
Evaluation of the capability to predict survival based on early changes in biomarker response showed that using the model-predicted changes in sVEGFR-3 based on longitudinal biomarker data from only the first 6 or 12 weeks of treatment (on average, 3.1 or 4.4 measurements per individual) resulted in a similar fit of the survival model as when using the full time course of sVEGFR-3 (ΔOFV ≤ 3).
Please notice that the adaptive algorithm we describe here is different from the branching logic used in many computerized tests to skip questions based on earlier patient responses.
With AUCInsulin 0-30)/AUCIRucose(0-30), CIR, AUCC-Peptide 0-30)/AUCC-Peptide 0-30 AUCC-Peptide 0-120)/AUCC-Peptide 0-120 IGI2, IGI1, and insulin 30 min, dynamic measures of insulin secretion based on early insulin and C-peptide responses to oral glucose represent measures which are more appropriate to assess genetically determined β-cell dysfunction than fasting measures, i.e., HOMA-B.
