Sentence examples for based on downregulation of from inspiring English sources

Anti-inflammatory actions of resolvins are largely based on downregulation of the recruitment and function of PMNLs and the decreased synthesis and secretion of proinflammatory mediators.

Transfection efficiency of miRNA in cell lines was confirmed based on downregulation of TWF1 (PTK9) mRNA following transfection with miR-1 as previously reported (Ichimi et al, 2009).

The transfection efficiencies of miRNA in PC3 and DU145 cells were confirmed based on downregulation of TWF1 (PTK9) mRNA following transfection with miR-1 as previously reported.

Transfection efficiency of pre-miR in cell lines was confirmed based on downregulation of TWF1 (PTK9) mRNA following transfection with miR-1 as previously reported (Ichimi et al, 2009).

The transfection efficiency of miRNA in cell lines was confirmed based on downregulation of TWF1 (PTK9) mRNA following transfection with miR-1 as previously reported(Kikkawa et al, 2010).

From this point of view, changes in melatonin receptor density in AD – increases in arterial MT1[ 274] and decreases in hippocampal MT2 [ 275] – may be less important than a remaining responsiveness of the SCN, perhaps in conjunction with the sedating effects of melatonin based on downregulation of neuronal NO synthase and actions on the GABAergic system [ 276].

Notch pathway downregulation was confirmed based on the downregulation of HES and HEY family members.

siRNA screens, in contrast to chemical biology screens, are based on the downregulation of the abundance of a particular protein.

These effects were based on a downregulation of the expression of c-fms and RANK, the receptors for monocyte-colony stimulating factor and RANKL, whereas MAP kinase, NF-κB or Akt signalling were not affected.

We evaluated the transfection efficiency of the miRNAs in cancer cell lines based on the downregulation of mRNA expression levels of protein tyrosine kinase 9 (PTK9, alias as twinfilin: TWF1) after miR-1 transfection.

The poor antitumor immunity and the escape to the innate and adaptive immune responses are based on the downregulation of tumor cell Major Histocompatibility Complex (MHC) I and costimulatory molecules, alteration of DCs and macrophages function in tumor tissue, regulatory T cells induction, and tumor-mediated immune cell death [ 4].