Sentence examples for based on disruption of from inspiring English sources
These findings and evidence based on disruption of the KmMIG1 gene (Cassart 1997) suggest that the negative regulation of KmINU1 is dependent on KmMig1p, a key effector for glucose repression as in strain CBS 6556.
Synthesis, structural and electrochemical elucidation of the C70(compounds) compounds are discussed, as well as electrochemically promoted switching of the electronic properties based on disruption of the conjugated 62π-electron system into the isolated 32 and 28π-electron fragments upon closing the [5,6]-bond.
The variant showed a mechanism of action based on disruption of GAG binding and oligomerization, that results in specific sequestration of CCL5 [2].
It seems therefore that there is a quantitative discrepancy with the previous data based on disruption of TRPC subunits.
These observations have provided new insights into opportunities for adjuvant therapies based on disruption of these processes.
PHMB is a membrane-active, cationic agent whose antibacterial mode of action is based on disruption of the bacterial cytoplasmic membrane and leakage of macromolecular components [ 6- 8].
The principle of SFP genotyping is based on the disruption of the hybridization of labeled DNA sequences that are genetically variable relative to a reference sequence used for design of probes on a microarray.
In fact, it is clear that, in spite of the initial enthusiasm, anti-angiogenic drugs, one of the most prominent examples of therapies based on the disruption of growth factors, have been disappointing.
Because the level of hypersecretion was lower than that expected based on the disruption of the AP-3 complex, we hypothesize that other classes of vacuolar enzymes involved in the degradation process may also require the AP-3 complex for correct sorting.
While mutations in the tll gene of Drosophila were first identified based on their disruption of anterior-posterior patterning, subsequent analysis demonstrated functions in embryonic CNS and larval eye development [ 19, 20].
