To increase the validity of our method we apply SVM classification on data extracted from ROIs based on disorder-specific metabolic reductions and atrophy reported in comprehensive meta-analyses investigating AD and FTLD.
This neuroimaging-aided approach allows the differentiation of diagnoses based on disorder-specific biological features.
In addition, some patients with persistent distress go on to develop a psychiatric disorder, notably major depression or anxiety disorder, based on specific vulnerabilities.
19): How sadly misguided for doctors to parse whether a person has a "genuine" eating disorder based on specific food behaviors or weights attained.
Based on several specific features in the disorder prediction scores, a predictor of helix-forming MoRFs was elaborated [ 34, 37].
As is the case for all psychiatric disorders, the diagnosis of attention deficit hyperactivity disorder (ADHD) is not based on a specific pathological agent, such as a microbe, a toxin, or a genetic mutation, but rather on the collection of signs and symptoms and evidence of impairment that occur together more frequently than expected by chance (Todd et al. 2005).
Given a scarcity of transgenic models for mitochondrial disorders chemically induced models, based on the specific and irreversible complex I inhibitor rotenone, have been used in studies of PD, AD and LHON.
Based on the specific features and patterns in the per-residue disorder propensity curves calculated by the PONDR ® VLXT tool combined with the analysis of several characteristic sequence-based parameters, short disordered regions capable of undergoing the disorder-to-order transitions on binding can be found by specific predictors.
We were then able to categorize the 12 phenotypes into two broad groups of ID/DD/MCA disorders and neuropsychiatric/behavioral disorders based on the age-specific prevalence within the cohort (Additional file 1: Figure S1).
Holmes et al. (2011) used a variant of the prospective imagery task in bipolar disorder that utilised a six-point rating scale for the vividness of each image from 1 (no image at all) to 6 (more vivid than reality) (sixth point added based on pilot work specific to this disorder).
GC: Is Dug based on a specific dog?
