Sentence examples for based on direct modifications from inspiring English sources

When drug resistance is mainly based on direct modifications of the target, as in the case with antifolates, an increase in drug quantity of the latter will probably be irrelevant, since it is unlikely that the number of drug molecules will overcome the number of target proteins (considering a regular stoichiometric relationship of action).

These networks are based on direct protein interaction data or protein modifications.

'Tree' is an ordinary, descriptive concept based on direct observation.

Scoring is based on direct observation of performance.

The sensitivity analysis was based on direct treatment costs.

INLA is based on direct numerical integration instead of simulations.

We conduct our analysis based on direct clinical comparisons.

Searching based on direct citations is not sufficiently comprehensive.

Information for patients should therefore be based on direct standardization.

However, this left-shift potential was not directly related to mechanical parameters, but rather based on a direct modification of electrophysiological properties.

Deployment of this simple assessment may be of greatest value in identifying and establishing a pool of cases that can then be used to develop even more sensitive test, based on specific peptide modification or on direct detection of pyrrole moieties in a blood sample.