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Diagnosis of this disease is based on direct identification or on cultivation of the parasite.
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Since the model is based on direct pattern identification within a network, it provides an efficient method to identify functional interaction or crosstalk between stimulation pathways (also referred to as 'structures') which can be used to define constraints for more detailed network reconstruction.
Moreover, this iterative search procedure should reduce the effect of fast evolving genomes and differences in the evolutionary rate of the examined species because the ortholog prediction is not merely based on direct ortholog identification starting from human, but predicting orthologs from more closely related species.
Tentative species identification, based on direct and indirect immunological methods, was available for serum, tissue, and urine specimens from 533 additional cases.
We assessed the ease of amplification and sequencing for these markers, examined the extent of the barcoding gap between intra- and inter-specific variation by pairwise distances, evaluated successful identifications based on direct sequence comparison of the "best close match" and the construction of a phylogenetic tree.
The increasingly high-throughput nature and declining costs of second-generation DNA sequencing have provided a durable solution for transcriptome analysis based on direct sequence evaluation through transcript discovery, identification of the transcriptional structure of a gene, detection of alternate splicing patterns, and quantification of expression levels [ 7, 8].
Identification of species was based on direct observations, tracks and other signs of activity (resting beds, feces).
The immediate identification of bacterial meningitis (BM) is based on direct examination of the cerebrospinal fluid (CSF) or the detection of bacterial antigens in the CSF.
Experimental approaches based on direct genome wide measurements of TFos are a powerful resource for the identification and analysis of TF binding sites.
Conclusion: A strategy based on direct examination of BAL fluid followed by the P55 cartridge when the former is positive allows rapid identification of pathogen in 80% of patients with VAP.
A direct strategy to inhibit survivin has been based on the identification of a specifically interacting peptide.
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