The impact of the lipophilic penetration enhancer, oleic acid (OA), on the barrier properties of stratum corneum (SC) lipid model membranes was investigated based on diffusion and permeation studies of model drugs covering a broad range of lipophilicities.
In order to broaden the range of matrices and implicitly to develop the class of drug delivery systems based on diffusion mechanism, in this study the starting materials, SBA-15 powder matrices, were engineered by MgO modification for antihypertensive drugs intercalation.
In line with this observation, a study based on diffusion tensor imaging has demonstrated a loss of asymmetry in schizophrenia for the uncinate fasciculus [11].
Whereas for Cd, Cu, and P only a few studies reporting diffusion coefficients based on diffusion cell experiments are available, there is a substantial number of literature data based on diffusion cell experiments for As V).
Recent advances in tractography allowed for more direct studies of anatomical network structure (white matter) based on diffusion tensor imaging and diffusion spectrum imaging [8] [10].
In the present study, both SC and FC changes were assessed based on diffusion weighted imaging (DWI) and resting-state functional MRI (rs-fMRI).
The microdialysis technique, based on diffusion of analytes across a semipermeable membrane, has been applied extensively to study TIF (for reviews, see [ 45- 52]).
For our analysis, we used kernels from six heterogeneous data sets that have been used for supervised interactive network inference in a previous study [ 1]: three based on protein sequence kernels and three based on diffusion kernels.
Curtis et al. (2012) built a microscale two-dimensional finite element model based on the diffusion studies of other porous materials to study the diffusion mechanism of natural gas in micro/nano-pores.
