Based on differential gene profiling in pterygium, it can be concluded that an aberrant wound healing process is the major pathogenetic process in pterygial formation.
This gold nanoprobe strategy relies on the colorimetric differentiation of specific DNA sequences based on differential aggregation profiles in the presence or absence of specific target hybridization.
We expect that within a coherent subnetwork, drugs and diseases are highly (anti-) correlated based on differential expression profiles.
We have followed a heuristic benchmarking approach to select a suitable unsupervised clustering method to group genes based on differential epigenetic profiles, while maximizing the biological interpretability of DEPs.
Marker discovery based on differential gene expression profiling, stringent sensitivity and specificity assays, and well-annotated patient samples can rapidly prioritise and identify novel MRD markers of NB (Cheung et al, 2008).
The top biological processes associated with genes clustered to gata3 with a correlation coefficient of at least 0.80, including cell proliferation and differentiation, apoptosis, cell cycle and intracellular signalling, correlated well with those identified in a dataset based on differential gene expression profiles in hair follicles from wild type and conditional gata3 null mice [26].
We describe a new algorithm 'Expression Signatures' for the classification of compounds based on differential gene expression profiles of cells treated with these compounds.
Here we report a first approach towards this goal, based on differential gene expression profiles for pre-pubertal and pubertal Spga and Sertoli cells, and defined transcript sets that characterize stem-ness and niche properties.
PFGE analysis performed on a subset of 71 S. Kentucky isolates generated 14 distinct PFGE profiles based on differential banding patterns.
RNA profiling assays based on differential display have been designed to overcome these difficulties and have been used to identify a set of 45 candidates usually down-regulated during apomictic development compared with sexual formation [ 23, 28].
