Sentence examples for based on denaturation under from inspiring English sources
Here we describe a modified strategy for the selection of stabilized antibody fragments by phage display, based on denaturation under reducing conditions.
Both mutants were found to be largely helical as per design, and based on thermal denaturation experiments, were substantially more stable than the MB-1 parent molecule.
We then developed and validated a separation method for hTα1 from E. coli cells based on thermal denaturation, nickel-resin affinity chromatography and high-performance liquid chromatography.
This technique is based on progressive DNA unwinding (denaturation) under highly controlled conditions of alkaline pH, time, and temperature.
The measurement of DNA strand breaks by FADU as described by Birnboim & Jevcak [ 1] is based on the partial denaturation ("unwinding") of double-stranded DNA under controlled alkaline conditions.
†Weighted mean based on population under surveillance.
This conclusion further supports our previous hypothesis (based on the thermal denaturation results, see above) that the trypotophan environments, despite their similar positions, are different in both proteins.
We have previously reported the use of PCR Melting Profile (PCR MP) technique based on using low denaturation temperatures during ligation mediated PCR (LM PCR) for bacterial strain differentiation.
"They're all based on AIDS cells under a microscope.
Moreover, kinetic analyses of DSC transitions based on a two-state denaturation model provide denaturation rates at 37°C for apoproteins in excellent agreement with those obtained from inactivation kinetics, indicating that DSC based kinetic analyses monitor irreversible denaturation and inactivation of apo-proteins [ 48].
This cellular bioassay is based on time-dependent alkaline denaturation of DNA under moderate denaturing conditions (pH 12.2 12.4) starting from ends as well as from all DNA break points (single-strand breaks, SSB; double-strand breaks, DSB; alkali-labile sites, ALS).
