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Based on deep sequencing of small RNA libraries and hybridization-based microarrays, Ugras et al. identified more than 40 miRNAs that were dysregulated in DDLS and not in normal adipose tissue and WDLS.
NGS strategies based on deep sequencing overcome some of the technical drawbacks of probe-based methodologies, especially the ability to detect only previously known sequences (Schulte et al. 2010).
It is based on deep sequencing of transcripts of interests to generate millions of short reads for analysis.
Our approach is based on deep sequencing of genomic libraries from selected progeny individuals.
We performed microbial profiling of samples based on deep sequencing of a 16S ribosomal gene region.
Therefore, based on deep sequencing data, our interpretation focuses on vision.
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RNA-seq, based on deep-sequencing techniques, has been widely employed to precisely measure levels of transcripts and their isoforms expressed under different conditions.
This small RNA quantification based on deep-sequencing was highly reproducible, as reflected by a high Pearson's correlation coefficient between miRNA levels of the two independent P0 tissue samples (r = 0.91).
Based on deep-sequence analysis of Pol II transcript 3′ ends, more than half of all yeast and human transcripts can be terminated at alternative poly(A) signals [50,217].
This however does not pose much problem to the tools based on deep-sequencing reads, as their methods are guided primarily by the sequences.
-,, Two main models of piRNA processing have been suggested based on deep-sequencing analysis of ovarian piRNAs.
More suggestions(15)
based on deep insight
based on genome sequencing
based on deep spiking
based on deep harmony
based on deep knowledge
based on deep thought
based on deep research
based on preliminary sequencing
based on deep noise
based on deep belief
based on deep reactive
based on deep suspicion
based on deep policy
based on deep learning
based on direct sequencing
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