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These annotations are based on data supporting different transcript isoforms; in most cases, there are no data addressing whether both protein isoforms are biologically relevant.
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This was based on data supported by data dictionaries which themselves were constrained to a dictionary definition specification.
Furthermore, the model selection framework employed here allows the explicit evaluation of model complexity based on data support.
Based on the data supporting these comparisons, it is clear that the one-to-one, interviewer-led setting (as used in the England study) is superior to the group, self-complete setting.
Based on preclinical data supporting the relevance of alpha-folate receptors in adenocarcinoma of the bronchioloalveolar carcinoma (BAC) subtype, this trial was designed to assess pemetrexed in patients with this pathologic subtype of lung adenocarcinoma.
This strategy was based on the data supporting maximum efficacy of reperfusion therapy given within 2 h of the onset of symptoms.
Based on sound data supporting the safety and efficacy of ArteFill, the U.S. FDA approved it for the treatment of nasolabial folds.
This observation is in agreement with recent classifications based on molecular data, supporting the classification of subfamilies Pitheciinae and Atelinae as sister groups included in the family Atelidae [ 8, 12].
Nevertheless, it is important to note that the regulatory limit does not include a safety factor; rather, it is based on available data supporting no observed adverse effect for methemoglobinemia in infants (the most sensitive subpopulation) [ U.S. Environmental Protection Agency EPAA) 1991].
Based on the data supporting the R-S domains, there was substantial indication that the inclusion of these items in the analysis would not influence examination of the other factors.
The generation of knowledge for "health system strengthening" requires qualified data, analytical skills and the ability to synthesize, adapt and disseminate evidence, therefore, the use of COPAS, can foster a culture based on scientific data, supporting decision making by managers aimed at developing sustainable health systems [ 30– 30].
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