Sentence examples for based on data demonstrating from inspiring English sources

Based on data demonstrating that, unlike F-actin bundles cross-linked with fimbrin which are very similar to those of microvillar core bundles, actin filaments cross-linked with villin are looser and less well-organized [17], [25], we conclude that villin's cross-linking activity is subordinate to that of fimbrin.

The 4-hour time point was principally selected based on data demonstrating that peak muscle IL-6 expression occurs between 4 8 hours post exercise [ 40].

Preference for using both options may be based on data demonstrating that combined therapy is superior to either monotherapy for prevention of recurrent bleeding from esophageal varices [ 19].

The upgrading of TCDD was based on data demonstrating that the multi-site carcinogenicity of this chemical in experimental animals was due to a mechanism involving activation of the aryl hydrocarbon receptor and studies showing that this receptor is highly conserved across species and functions the same way in humans and in experimental animals.

Based on initial data demonstrating the immunstimulatory potential of PstS-1 on PBMC's and dendritic cells [ 10] we addressed the influence of PstS-1 on purified NK cells and monocytes and investigated whether the addition of PstS-1 to the NK-monocyte-co-culture would lead to further enhancement of different NK cell functions.

A time frame of 24 h was chosen based on previous data demonstrating significant diaphragm atrophy, proteolysis, and oxidative stress after this interval [15].

The knee examination components were selected based on recent data demonstrating the potential for reproducibility across examiners [ 27].

Treatment targets and algorithms were common for the intensive treatment group in all centres and were based on trial data demonstrating the benefits of intensive treatment of cardiovascular risk factors in people with Type 2 diabetes [ 1, 2, 24– 26].

Based on such data demonstrating equivalence of these two treatment options, the American Academy of Neurology has concluded that TPE and IVIg are equivalent and recommended either for the treatment of non-ambulatory patients [ 5].

Based on our data demonstrating that apoptosis is induced even in DAOY cells following KDM1A knockdown, we suggest that KDM1A inhibition can circumvent the blockade of BMP2-mediated apoptosis in medulloblastoma cells incapable of responding to retinoids.

2. Treatment algorithms: These were based on trial data demonstrating the benefits of intensive treatment of several cardiovascular risk factors in people with diabetes [ 35- 38], and recommended medication within licensed indications (Table 1).