28 Importantly, based on current clinical trial outcomes, MSC therapy appears safe.
The quality of evidence, based on current clinical trials, was graded as very low [ 40]. a according to the GRADE-scale, see Table 1.
Therefore, based on current information, further clinical trials comparing early vasopressor support plus fluid resuscitation versus fluid resuscitation alone are warranted.
Based on current evidence obtained from clinical trials, HRT increases risk for breast cancer, stroke, and other adverse health outcomes.
To decrease the burden of chronic diseases, treatment guidelines have been developed based on current best evidence from large clinical trials.
Based on current evidence, the minimum acceptable SpO2 reading for this trial is 91% [ 44].
For each question, participants chose among four to six proposed answers, which were based on current national and international recommendations and evidence from published trials.
This practical framework is based on current evidence but remains to be formally supported by randomized prospective trials.
The doses were chosen based on current market availability of the respective treatments and the doses used in the clinical trials.
In this trial we want to implement a cognitive based education programme, which is theoretically based on current understanding and knowledge of pain mechanisms.
