Sentence examples for based on crystal structure from inspiring English sources

Based on crystal structure data, the PP2A structural subunit, PR65, is a C-shaped protein composed of two layers of helices and the flexible linker region between the helices forms a ridge on one edge of the structure (Cho and Xu, 2007; Xu et al., 2006; Xu et al., 2008).

Based on crystal structure analysis by particle swarm optimization methodology, NaBC is predicted to crystallize in the layered P63/mmc crystal structure as LiBC.

The design was based on crystal structure information and a comparative study of several electrophilic warheads.

In this study, we constructed human topoisomerase II alpha (hTop2α) homology model docked with Amsacrine based on crystal structure of human Top2β in complex with etoposide.

In another example, a homology model of M1 acetylcholine receptor (mAChR) based on crystal structure of bovine rhodopsin, served for VS and led to development of a series of novel 1- N-substituted piperidin-4-yl) benzimidazolones [53].

Binding mode analysis of a series of molecules having characteristic molecular geometry, flexibility and basicity was conducted based on crystal structure of the inhibitory DNA (iDNA) bound to horse and bovine TLR9.

This agonistic effect was further confirmed in silico using a prediction model based on crystal structures.

Further NMR binding kinetics study and enzymatic assays of the mutants are required to confirm our conclusion based on crystal structures.

Based on crystal structures of the isolated heme-binding domain, it is suggested that the FG loop is involved in intra-molecular signal transduction to the catalytic domain.

We used computer modeling based on crystal structures to illustrate the potential structures of the three constructs (Figure 1B).

The theoretical ΔH (ΔHcalc) based on crystal structures were obtained using well-known structure-energetics relationships [20], [21] as described previously [22].