Sentence examples for based on copy number from inspiring English sources

We have described a network-based integrative method for discovering disrupted pathways based on copy number alterations in human cancers.

Based on copy number alterations and transcriptional profiles, the posterior fossa tumors (medulloblastoma (MB), ependymoma and pilocytic astrocytoma) have been classified into various subgroups.

Fig. 4 Comparison of the transpositional rate of 52 Ty1-copia and 57 Ty3-gypsy families based on copy number distribution, plotted against the genome size of each Oryza species.

Each column represents an individual patient, colour-coded based on copy number aberration (amplification or deletion) and/or mutational state (truncating mutation, inframe mutation, missense mutation) across profiled oncogenes and suppressors frequently altered in lung adenocarcinoma.

An additive term for the haplotype of interest was coded as 0, 1, or 2 based on copy number present.

Interactive effects between the maternal ATCA COMT haplotype and maternal MTHFR and the fetal ATCA COMT haplotype and fetal MTHFR were tested using multiple logistic regression in R. The MTHFR was included as an additive term coded as 0, 1, or 2 based on copy number of the minor "T" allele.

Based on copy numbers estimated for other schistosome retrotransposons (see [ 13]), we consider that Sinbad is not a high copy number element.

Using two-dimensional unsupervised hierarchical clustering analysis based on copy numbers and all array CGH probes, the 49 UCs were clustered into three subclasses, clusters A, B1 and B2, which contained 4, 12 and 33 tumors, respectively.

Results from methylation analysis were compared with DNA copy numbers based on TaqMan copy number analysis of loci representing chromosomal regions 11q, 16q, 18p, and 18q published for case 1 32 in the same tumor series.

Each RAR marker was coded as 0 or 1 based on the copy number status; 0 indicates no copy number variation and 1 indicates copy number change in the marker region.

Various clustering methodologies have been applied to comparative genomic hybridization (CGH) data sets to classify cancers based on their copy number patterns and identify copy number aberration hotspots [ 17- 23].