Next, we identified robust Wnt target genes based on consistent changes in a combination of experiments (details not shown): lithium chloride inhibition of GSK3β 21 in the normal RIE-1 intestinal cell line (Leedham, unpublished data, 2010) and exon mRNA expression microarray and qRT-PCR in tumours from Apc-mutant mice.
In a previous study, of the animals in the present study 1, which sought to predict the relationship between detection of PrPd and incubation period according to dose, the clinical criteria were based on the combination of clinical signs consistent with the "definite" clinical diagnosis of BSE which was considered equivalent to reporting of the animal as a suspect in the field [ 13].
Consistent report of diabetes was defined based on the combination of response rate to the yearly questionnaire and frequency of self-reports of diabetes in the completed questionnaires.
"Park wildlife biologists recommended euthanasia of the bear based on a combination of factors including the presence of dental injuries consistent with the hiker's bite wound, the size and gender of the bear, and being the first and only bear present near the scene of the attack," said a park news release cited by National Parks Traveler.
The selection and expansion of SMRU's research population was consistent with 'research for health justice', as it was based on a combination of the border population's poor health and need for clinical research.
It is shown by simulations that the proposed selective soft combination-based scheme significantly outperforms the conventional non-selective schemes based on soft combination and 1-bit hard combination.
The assignment of an MLVA type was based on the combination of repeat counts for VNTRs 1, 3a, 3b, 4, 5, and 6 and was consistent with international nomenclature.
