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Metabolic pathways were predicted and reconstructed based on conserved pathways in the KEGG and MetaCyc (Caspi et al. 2014) databases and UniProtKB (UniProt Consortium 2014) together with pathways predicted for endosymbionts (Shigenobu et al. 2000; Koga and Moran 2014; Nikoh et al. 2014; Santos-Garcia, Latorre et al. 2014).
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The phylogenetic reconstruction was based on conserved domains.
In silkworm, cuticular protein genes are divided into five families based on conserved motifs.
We specifically present a method based on a graph-matching algorithm to detect conserved pathways between two protein networks.
Based on the previous sections, we ask if functionally conserved pathways can be used to identify the possible recruitment patterns in the metabolism of Gammaproteobacteria.
They carefully distinguished synteny, which they were basing on conservation of function, from conserved segments, based on conservation of sequence.
We evaluated the evolutionary conservation of each pathway map, based on the conserved orthologous genes derived as above.
Drosophila peripheral nervous system dendritic arborization (da) neurons, classified into four classes (I IV) based on their location and dendritic arbor complexity, have served as a powerful model system for studying conserved pathways controlling dendrite morphogenesis (Parrish et al., 2007).
Conserved residues are shaded by different intensities based on conservation level in the alignment.
Primers were designed based on highly conserved iridoviral sequences.
Such diversity confounds interpretations of prevalence data based on relatively conserved 18S rRNA sequences.
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