Sentence examples for based on conserved co-expression from inspiring English sources

Analysis of co-expression maps can also reveal the preserved interactions in sets of genes known to be associated with a certain condition or function [ 19], and using a method based on conserved co-expression, the most diverged and conserved GO categories have been recently listed [ 20].

The associations of these proteins with others are solely based on (conserved-) co-expression data, indicating involvement in the same process, without any evidence for potential physical associations.

MetaGene consists of 22,163 evolutionary conserved co-expression relationships from humans, flies, worms, and yeast, based on the analysis of over 3182 published DNA microarray experiments by Stuart et al [ 43].

On the other hand, we use conserved co-expression to assess inter-species annotation transfers suggested by borderline sequence similarity.

All two gene combinations were assessed for potential conserved co-expression.

These pairs have conserved co-expression across the molecular levels.

Based on this procedure, an empirical null distribution of random EC scores, genes that exhibit a statistically significant low EC score can be derived by calculation of Z-scores: genes with a positive EC score and a Z-score ≥1·96 comprise genes with highly conserved co-expression relationships.

We evaluated conserved co-expression networks using known meiotic genes annotated by gene ontology (GO 0007126) [ 20].

Our future direction will include testing conserved co-expression metagene pairs common to multiple networks.

An alternative to our approach is to cluster Pearson correlation matrix to identify conserved co-expression.

We also examined conserved co-expression pairs using enriched genomic information in yeast.