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That's highly questionable based on consensus predictions about the arc of AI innovation.
We created a dataset of 13,208 human membrane proteins based on consensus predictions of α-helices with three applications, Phobius [ 12], TMHMM [ 2], and SOSUI [ 13], in all 69,731 sequences in the human proteome dataset provided by IPI (v3.39).
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A composite classification scheme based on consensus TM prediction was employed to select representative ORs from each cluster.
The secondary structures of the extreme N and C terminal regions of all AtpD homologs not covered by crystal structures were predicted bases on consensus predictions from psipred [ 45] and Porter [ 46].
Based on consensus secondary structure prediction of the second and third cytoplasmic loop we noted that mutations resulting in unstable protein variants predominantly reside in regions that are predicted to adopt an α-helical structure.
Targeting predictions based on consensus of at least two algorithms indicated that ∼24% of the proteins are mitochondrial, ∼19% are cytosolic, and ∼5.4% are nuclear.
Similarly, predictions based on consensus of multiple analysis results are generally more robust and perform better than any single method [ 52].
This motivated us to employ an improved approach for target prediction based on consensus of tools and multiple statistical steps.
NetPhos and Scansite are online search tools that enable prediction of phosphorylation sites based on consensus sequences defined in vitro (27, 28).
Based on consensus estimates, it stands at 13.
All agreements were based on consensus.
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