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Different computational approaches related to the drug repositioning problem have been proposed, ranging from clustering drugs either based on their pharmacophore descriptors [ 6] or based on connectivity map-based networks [ 7] to predicting drug-target interactions [ 8– 10] and drug-disease associations [ 11– 15].
The computations based on connectivity metrics are explained for each of these three approaches.
These interactions are quantified based on connectivity and response sensitivity information.
We label the semantic relations between categories using methods based on connectivity in the network and lexico-syntactic matching.
To identify brain sulci, sulcal images were generated by morphologic operations and then separated into different components based on connectivity analysis.
In contrast, the atrium of the international building was envisioned as a public plaza based on "connectivity — inviting the world in," said Shirley Blumberg, partner-in-charge for KPMB Architects, the Toronto firm that designed the project.
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Our aim was to establish a population-based mask of the FPC based on connectivity-based parcellation.
We explain the results based on the connectivity, or dis-connectivity, between terrestrial carbon sources and pathways for sediment transport.
Connectivity filters identify nodes based on their connectivity levels.
The second step is disassembling connected components based on pixel connectivity.
After ensuring that the connectivity graph is connected, the gateway builds the SPT based on the connectivity graph.
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