Sentence examples for based on conformational changes from inspiring English sources

Furthermore, based on conformational changes observed for Uba2 at earlier steps in the Sumo activation cycle, it seems that the Uba2 cysteine domain may also undergo conformational changes to meet the Ubc9 cysteine for Sumo transfer [20].

Therefore, APC differs from AGC, which has a regulatory mechanism based on conformational changes within a dimeric regulatory domain.

The switching mechanism on electrically switchable oligopeptide surfaces is based on conformational changes between collapsed ("OFF" state) and fully extended ("ON" state) oligopeptide structures.

The use of polymers as building blocks for surface modification allows the preparation of "smart" or responsive surfaces that operate based on conformational changes in the polymer backbones.

Parenthetically, we note that although the model described above is based on conformational changes that occur in the ketosynthase domain, the ACP domain could also undergo additional (perhaps complementary) changes, as suggested for the case of nonribosomal peptides by Marahiel and co-workers.

In examples, the strategy and the application of small molecule-based FRET probes for the detection of enzymes involved in bond formation and hydrolysis including proteases and lipases, protein substrate interaction, as well as sensors based on conformational and environmental changes are discussed.

During Data Pre-Processing descriptors based on conformational ensembles are computed and stored in a database.

A colorimetric biosensor for DNA screening was designed based on the conformational changes of the horseradish peroxidase (HRP -mimicking DNAzyme.

To achieve the direct detection of OTA, aptamer conjugated redox probe was used and detection was demonstrated based on the conformational changes in aptamer structure upon OTA sensing.

Here, we report a DNA machine for selective Gquadruplex-binding ligand recognition, based on a conformational change; the forces exerted by the precise DNA machine for Gquadruplex conformational change were probed via an electrical signal transducer electrochemically by differential pulse voltammetry and cyclic voltammetry.

A model based on a conformational change must alter calcium binding affinities to account for changes in calcium sensitivity.