Sentence examples for based on computational studies from inspiring English sources
Based on computational studies, some analogues were synthesized and subjected to pharmacological evaluation involving antioxidant activity, toxicity and memory model studies in animals followed by detailed mechanistic in vitro cholinesterase inhibition study.
In terms of translational research, two aspects, that is, biomarker discovery and drug design for diagnosis or treatment of diseases, were discussed based on computational studies.
Crystal structure analysis revealed an anion receptor 'nest' motif in these inhibitors, which based on computational studies was shown to interact with helical monomers of hIAPP.
Other suggestions based on computational studies have been (iii) that protonation of the metal cofactor bound OH− may occur, thus impeding hydroxyl rebound [33].
The design was based on computational docking studies using the extracted active site of fVIIa.
The binding site for these drugs is well established and they were designed based on computational docking studies.
Consistent to the prediction based on computational modeling studies, a lack of RelA p52 dimer generation in Nfkb2 −/− cells, however, ablated LTβR-mediated enhancement of TLR4-induced late RelA DNA binding activity as well as crosstalk amplification of RelA target pro-inflammatory gene expressions (bottom panel, Figure 4H).
Based on computational modeling and field studies, the 'steep, deep, and cheap' ideotype proposed by Lynch and colleagues may provide advantages to the plant for capturing water and elements like nitrogen that are water soluble and therefore tend to move in the soil column with water.
More sophisticated methods based on computational intelligence are also studied for developing credit scoring models.
This integrated procedure is used for various woven and 3D RVEs to illustrate its versatility, showing that the discretized RVEs can be used for parametric studies based on computational homogenisation.
Different studies based on computational analysis on both expressed sequence tags and high-throughput RNA sequencing provide an estimate of the frequency of these events.
