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Some of these approaches are based on computational simulation models (e.g. Epstein 1999 and Hare and Deadman 2004), while others have followed a more deliberative approach (Soncini-Sessa et al. 2007 and Cohen and Neale 2006).
The model was based on computational simulation of thermal denaturation of rhodopsin that had predicted the existence of a folding core involving loops and TM helices near the extracellular (EC) surface of rhodopsin.
Based on computational simulation using publically available methylation data, we additionally show that future studies comparing two groups of PDXs should use 15 or more samples in each group to minimise the impact of xenografting-associated changes in methylation on comparison results.
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The daylighting analysis was based on computational simulations with daylighting programs, for different combinations of days, schedules and building solar orientations.
This study demonstrates a pathway of materials search based on computational simulations for proper media that can hold hydrogen at ambient conditions through physisorption.
Furthermore, we show based on computational simulations that it is possible to derive both the presence and absence of reflexive attraction from the same retrieval mechanism, based on the ACT-R architecture.
Free energy calculations based on computational simulations of protein carbohydrate complexes have also been employed to investigate antigenicitiy of carbohydrate antibody interactions (Pathiaseril and Woods 2000).
Moreover, Zhan et al. [ 2012] recently demonstrated the improvement of DOT image quality based on computational simulations when a whole-brain spatial constraint and SVR were used simultaneously.
Based on computational simulations, Dar et al. [ 6] reasoned that increasing the noise level of gene expression might have synergistic effects with conventional transcriptional reactivators to enhance HIV reactivation from latency.
The experimentally measured value reported here (5 × 10−10 m2) is in good agreement with predictions based on Computational Fluid Dynamics simulation and broadly consistent with the Carman Kozeny empirical estimate.
In essence, detailed and computationally demanding analyses – based on computational fluid dynamics simulations (CFD) of the reactor – are first used to study in detail a selected and limited number of conditions.
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