Sentence examples for based on compounds that from inspiring English sources
The fluorescence intensity of GFP-Ipr1 at 0.2 U/mL IFNγ was set as a threshold for our gating and we selected hits based on compounds that showed at least four fold increase in GFP-Ipr1 signal above the background.
In the present work, we built and analyzed a drug target network based on compounds that have been documented to elicit tinnitus as side effect, in order to explore the tinnitus target space.
The discovered potency of PJ-34 in preventing bipolar clustering of extra centrosomes in mitosis may pave the way for a new efficient therapy lacking intolerable side effects, which is based on compounds that exclusively target the unique dependence of many human cancer cells on their supernumerary centrosomes clustering for their survival.
The structures of 10 ligands were based on pyridine compounds that possessed thioalkyl substituents containing a primary amine, which was required for immobilisation of the ligands onto an epoxy-activated matrix (epoxy-Sepharose Fast Flow®).
Few people realize that half of all new medicines are based on chemical compounds that come from nature.
A reasonable approach to understand these results is based on testing compounds that would prevent (or reverse) impairment of cognitive functions and simultaneously block neurodegeneration, and/or oligomerization of Aβ.
Furthermore, it explains why lung cancer and other solid tumours are completely refractory to treatments based on these compounds that are effective therapies for some types of leukaemia.
The most common MRI contrast media are based on paramagnetic compounds that contain metal ions from the transition or lanthanide series of the periodic table such as manganese, iron and gadolinium.
Our work is based on compounds with the same monastrol scaffold, that are, 37 newly synthesized 3, 4-dihydropyrimidin-2(1H -one (or thione) derivatives (see structures in Table 1H -one
However, based on compounded error, values that vary by less than 50% within assays, and by less than 70% in separate assays could not be clearly separated.
Based on known compounds that block chloride channels, we suggest that the absence of negative charged amino acids on AaCtx structure may be responsible for its weak activity on glioma cells migration and invasion.
